A new article by Matthew Dacso, Kara McArthur, and Clifford Dacso on the website of The Scientist explains how economic and social inequality have epigenetic ramifications and how those, in turn, aggrandize health disparities. As SARS-CoV-2 continues to ravage the world, its disproportionate effect on those of lower socio-economic status is both a reminder of this fact and a call to action.